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Milly is the woman who has everything: a successful career, a rock-star husband, and two beautiful children. Her best friend, Jess, works in a community garden, lives in a boathouse with her boyfriend Jago, and desperately wants a baby. Jess and Milly can't remember a time they didn't share everything - secrets, clothes, even boyfriends. That is, until Milly is hit with the life-changing news that she has breast cancer and needs Jess's support more than ever. As Jess tries to balance her own life as well as being there for Milly, it is only a matter of time before the pressure on their bond takes its toll.