After being the only survivor of the crash of Flight 180, Clear Rivers has locked herself away in the perceived safety of a psychiatric hospital, where she lives in constant terror that Death is coming to claim her, as it did all her friends. Clear may be considered crazy, but she's not wrong. Death is moving toward suburban Route 23, heading south. En route to a weekend getaway with her friends, Kimberly Corman watches helplessly as a logging truck careens out of control and loses its deadly payload, setting off a horrifying chain reaction that leaves twisted metal and dead bodies in its wake--including her own. A moment later, Kimberley finds herself still stuck in on-ramp traffic, with a line of commuters she saw die moments before. It was only a vision, but was it a warning? Shocked into action, Kimberly blocks the cars from joining the traffic on Route 23. The commuters begin to honk and complain--until Kimberly's premonition comes true. Death tears up the highway in a massive pile-up, with those left on the on-ramp narrowly escaping with their lives. But Kimberly knows it s not over. Death will not be cheated so easily for this random group of strangers who must join Kimberly in a race against time to do what all but one of the survivors of Flight 180 couldn't--stay alive.