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Brian and Charles follows Brian, a lonely inventor in rural Wales, who spends his days building quirky, unconventional contraptions that seldom work. Undeterred by his lack of success, Brian attempts his biggest project yet. Three days, a washing machine, and various spare parts later, he's invented Charles, an artificially intelligent robot who learns English from a dictionary and has an obsession with cabbages. What follows is a humorous and entirely heartwarming story about loneliness, friendship, family, finding love, and letting go.